2022 Fall ADRC Meeting

Fall ADRC Meeting Oct 20 - 21, 2022
Fall ADRC Meeting Oct 20 - 21, 2022

Meeting Recordings and Presentation Slides Are Now Available
You can also enjoy a quick scroll through attendee submitted photos!

    Fall ADRC Meeting Highlights

    The Fall 2022 ADRC Meeting was held in a Hybrid format, online and in-person in Chicago, Il. Links to slides and video recordings are below.

    Location: Swissotel, Chicago Illinois

    In Attendance:

    • In-person: 277
    • Virtual: 657

    Meeting Theme: Diversity Equity and Inclusion

    The Fall ADRC Meeting centered on the importance of Diversity, Equity, and Inclusion (DEI) in ADRC research and operations, which was intended to set the stage for increased efforts network-wide to ensure equitable practices and increased representation of the communities we serve. This is a stated priority of the NIA and of our Center members.
    The DEI focus of the 2022 Fall ADRC Meeting:
    • Understanding the scientific underpinnings of potential racial and ethnic differences in the pathobiology and clinical phenotye of ADRD
    • Examining and addressing why some minoritized populations are disproportionately underdiagnosed and affected by ADRD
    • Assessing the possible relationship between lifelong social exposures and risk and resilience to ADRD
    • Diversifying the ADRC participant pool
    • Cultivating a diverse ADRC workforce

    Directors Session

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    NIA Update
    Richard Hodes, MD NIA
    ADRC Program Update
    Nina Silverberg, PhD NIA
    NACC Update
    Walter Kukull, PhD NACC
    NCRAD Update
    Tatiana Foroud, PhD NCRAD
    NIAGADS Update
    Li-San Wang, PhD Penn ADRC / Penn Memory Center
    Social Determinants of Health and Health Equity
    Lisa Barnes, PhD Rush University Alzheimer's Disease Center
    Genetics of Alzheimer's Disease in Minoritized Populations
    Margaret Pericak-Vance, PhD John P. Hussman Institute for Human Genomics
    Impact of Race and Ethnicity on AD Biomarkers
    Michelle Mielke, PhD Wake Forest University ADRC
    Closing Remarks
    Sanjay Asthana, MD, Fabu Carter, PhD Wisconsin ADRC
    NIA Update
    Richard Hodes, MD NIA
    ADRC Program Update
    Nina Silverberg, PhD NIA
    NACC Update
    Walter Kukull, PhD NACC
    NCRAD Update
    Tatiana Foroud, PhD NCRAD
    NIAGADS Update
    Li-San Wang, PhD Penn ADRC / Penn Memory Center
    Social Determinants of Health and Health Equity
    Lisa Barnes, PhD Rush University Alzheimer's Disease Center
    Genetics of Alzheimer's Disease in Minoritized Populations
    Margaret Pericak-Vance, PhD John P. Hussman Institute for Human Genomics
    Impact of Race and Ethnicity on AD Biomarkers
    Michelle Mielke, PhD Wake Forest University ADRC
    Closing Remarks
    Sanjay Asthana, MD, Fabu Carter, PhD Wisconsin ADRC

    Data Core Session

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    Introduction
    Sudeshna Das, Phd Massachusetts ADRC
    Developing Digital Assessments for Down Syndrome-Associated AD
    Jason Hassenstab, PhD Washington University Knight ADRC
    Taking Digital Measures from Validation to Scaling to Researcher Tools Collecting Data on 500k Participants
    Larsson Omberg, PhD Sage Bionetworks
    Opportunities and Challenges in Using Digital Biomarkers as Trial Outcomes
    Hiroko Dodge, PhD Oregon Health and Science University ADRC
    Impact of the COVID-19 Pandemic on Enrollment at United States Alzheimer's Disease Research Centers
    C. Elizabeth Shaaban, PhD, MS, MPH University of Pittsburgh ADRC
    CDR Domain Scoring Variation by Race in the NACC Dataset
    Giovanna Pilonieta, PhD, DDS, MPH UAB Exploratory ADRC
    Introduction
    Sudeshna Das, Phd Massachusetts ADRC
    Developing Digital Assessments for Down Syndrome-Associated AD
    Jason Hassenstab, PhD Washington University Knight ADRC
    Taking Digital Measures from Validation to Scaling to Researcher Tools Collecting Data on 500k Participants
    Larsson Omberg, PhD Sage Bionetworks
    Opportunities and Challenges in Using Digital Biomarkers as Trial Outcomes
    Hiroko Dodge, PhD Oregon Health and Science University ADRC
    Impact of the COVID-19 Pandemic on Enrollment at United States Alzheimer's Disease Research Centers
    C. Elizabeth Shaaban, PhD, MS, MPH University of Pittsburgh ADRC
    CDR Domain Scoring Variation by Race in the NACC Dataset
    Giovanna Pilonieta, PhD, DDS, MPH UAB Exploratory ADRC

    Clinical Task Force (CTF) Session

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    Introduction
    Allan Levey, MD, PhD Emory University, Goizueta ADRC
    MBI Update
    Howie Rosen, MD & Constantine Lyketsos, MD UCSF & Johns Hopkins ADRCs
    SCD Update
    Lisa Barnes, PhD & Andrew Saykin, PsyD Rush University Alzheimer's Disease Center & Indiana University ADRC
    Closing Remarks
    Allan Levey, MD, PhD Emory University, Goizueta ADRC
    Introduction
    Allan Levey, MD, PhD Emory University, Goizueta ADRC
    MBI Update
    Howie Rosen, MD & Constantine Lyketsos, MD UCSF & Johns Hopkins ADRCs
    SCD Update
    Lisa Barnes, PhD & Andrew Saykin, PsyD Rush University Alzheimer's Disease Center & Indiana University ADRC
    Closing Remarks
    Allan Levey, MD, PhD Emory University, Goizueta ADRC

    Outreach Recruitment and Engagement (ORE) Core Session

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    Introduction
    Laura Baker, PhD Wake Forest University ADRC
    Building Strong, Bi-directional, and Sustainable Community Partnerships to Support Recruitment for AD Trials
    Gina Green-Harris, MBA Wisconsin ADRC
    Ethical Considerations Associated with Financial Compensation of Participants and Study Partners
    Emily Largent, PhD, JD, RN Penn ADRC / Penn Memory Center
    Panel Discussion
    Sophia Wang, MD (moderator) Indiana University ADRC
    ORE Core Session Take Home Messages
    Corinne Pettigrew, PhD Johns Hopkins ADRC
    Introduction
    Laura Baker, PhD Wake Forest University ADRC
    Building Strong, Bi-directional, and Sustainable Community Partnerships to Support Recruitment for AD Trials
    Gina Green-Harris, MBA Wisconsin ADRC
    Ethical Considerations Associated with Financial Compensation of Participants and Study Partners
    Emily Largent, PhD, JD, RN Penn ADRC / Penn Memory Center
    Panel Discussion
    Sophia Wang, MD (moderator) Indiana University ADRC
    ORE Core Session Take Home Messages
    Corinne Pettigrew, PhD Johns Hopkins ADRC

    Neuropathology Core Session

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    Welcome and Survey Update
    Andrew Teich, MD Columbia University ADRC
    NeuroBioBank Update
    C. Dirk Keene, MD, PhD University of Washington ADRC
    Microglial Heterogeneity in Cognitively Resilient Individuals from the Mayo Clinic Study of Aging
    Aivi Nguyen, MD Mayo Clinic ADRC
    Proteomic Studies on the Phosphorylated Tau Interactome in the Human Brain of Alzheimer's Disease
    Arline Faustin, MD NYU ADRC
    Computer Vision & Machine Learning in Digital Neuropathology
    Kurt Farrell, PhD Mount Sinai School of Medicine ADRC
    Narratives and Storytelling in DEI: The Diversify In Path Podcast experience
    Michael Williams, MD UAB Exploratory ADRC
    The Neighborhoods Study: Linking the Disparities-Aligned Exposome to Brain Tissue
    Amy Kind, MD, PhD Wisconsin ADRC
    Welcome and Survey Update
    Andrew Teich, MD Columbia University ADRC
    NeuroBioBank Update
    C. Dirk Keene, MD, PhD University of Washington ADRC
    Microglial Heterogeneity in Cognitively Resilient Individuals from the Mayo Clinic Study of Aging
    Aivi Nguyen, MD Mayo Clinic ADRC
    Proteomic Studies on the Phosphorylated Tau Interactome in the Human Brain of Alzheimer's Disease
    Arline Faustin, MD NYU ADRC
    Computer Vision & Machine Learning in Digital Neuropathology
    Kurt Farrell, PhD Mount Sinai School of Medicine ADRC
    Narratives and Storytelling in DEI: The Diversify In Path Podcast experience
    Michael Williams, MD UAB Exploratory ADRC
    The Neighborhoods Study: Linking the Disparities-Aligned Exposome to Brain Tissue
    Amy Kind, MD, PhD Wisconsin ADRC

    Cross Core Collaborative Session 1: Research Translation for All Persons: A Discussion of the ADRC Network Role

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    A Personal Perspective: The Importance of Equal Access to Care and Intervention in AD
    Maria Carrillo, PhD Alzheimer's Association
    The Case of Exercise Interventions
    Laura Baker, PhD Wake Forest University ADRC
    The NIA Perspective
    Patricia Jones, PhD NIA
    Discussion
    Amy Kind, MD, PhD (moderator) Wisconsin ADRC
    A Personal Perspective: The Importance of Equal Access to Care and Intervention in AD
    Maria Carrillo, PhD Alzheimer's Association
    The Case of Exercise Interventions
    Laura Baker, PhD Wake Forest University ADRC
    The NIA Perspective
    Patricia Jones, PhD NIA
    Discussion
    Amy Kind, MD, PhD (moderator) Wisconsin ADRC

    Cross Core Collaborative Session 2: The Diversification of Brain Tissue: Why and Ways Forward

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    Amplifying Facilitators and Addressing Barriers: The Development and Implementation of Strategies to Increase Brain Donation Among Demographically Diverse Older Adults
    Crystal M. Glover, PhD Rush University Alzheimer's Disease Center
    Amplifying Facilitators and Addressing Barriers: The Development and Implementation of Strategies to Increase Brain Donation Among Demographically Diverse Older Adults
    Crystal M. Glover, PhD Rush University Alzheimer's Disease Center

    Data Core Pre-Meeting Workshop

    View the Full Session on Youtube:
    View and Download Slide Presentations:
    Bayesian random change point mixed model for longitudinal data: an application to the study of cognitive performance trajectories in Wisconsin Registry for Alzheimer's Prevention
    Lianlian Du, MS Wisconsin ADRC
    Statistical Methods For Assessing Health Disparity in Longitudinal ADRD Research
    Chen-Pin Wang, PhD South Texas ADRC
    Development Update
    Deborah Zemlock Northwestern ADRC
    Requirements Update
    Chard Murchison, PhD, and Sarah Gothard, PhD UAB Exploratory ADRC, and Oregon Health and Science University ADRC
    Bayesian random change point mixed model for longitudinal data: an application to the study of cognitive performance trajectories in Wisconsin Registry for Alzheimer's Prevention
    Lianlian Du, MS Wisconsin ADRC
    Statistical Methods For Assessing Health Disparity in Longitudinal ADRD Research
    Chen-Pin Wang, PhD South Texas ADRC
    Development Update
    Deborah Zemlock Northwestern ADRC
    Requirements Update
    Chard Murchison, PhD, and Sarah Gothard, PhD UAB Exploratory ADRC, and Oregon Health and Science University ADRC